FTH1 Antibody (PACO14080)
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주문- SKU:
- PACO14080
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FTH1 Antibody (PACO14080) |
Antibody SKU: | PACO14080 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human FTH1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14080(FTH1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14080(FTH1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. |
Synonyms: | Ferritin, heavy polypeptide 1 |
UniProt Protein Function: | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. |
NCBI Summary: | This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02794 |
NCBI GenInfo Identifier: | 120516 |
NCBI Gene ID: | 2495 |
NCBI Accession: | P02794.2 |
UniProt Secondary Accession: | P02794,Q3KRA8, Q3SWW1, B3KNR5, |
UniProt Related Accession: | P02794 |
Molecular Weight: | |
NCBI Full Name: | Ferritin heavy chain |
NCBI Synonym Full Names: | ferritin, heavy polypeptide 1 |
NCBI Official Symbol: | FTH1 |
NCBI Official Synonym Symbols: | FHC; FTH; HFE5; PLIF; FTHL6; PIG15 |
NCBI Protein Information: | ferritin heavy chain |
UniProt Protein Name: | Ferritin heavy chain |
UniProt Synonym Protein Names: | Cell proliferation-inducing gene 15 protein |
Protein Family: | Iron transporter |
UniProt Gene Name: | FTH1 |
UniProt Entry Name: | FRIH_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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