FST Antibody (PACO64239)
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주문- SKU:
- PACO64239
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | FST Antibody (PACO64239) |
Antibody SKU: | PACO64239 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:1000-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Follistatin protein (30-344AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: U251 whole cell lysate. All lanes: FST antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39, 35 kDa. Observed band size: 39 kDa. |
Background: | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
Synonyms: | Follistatin (FS) (Activin-binding protein), FST |
UniProt Protein Function: | FST: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: cytoplasm; extracellular region; nucleus Molecular Function:heparan sulfate proteoglycan binding; signal transducer activity; protein binding; activin binding Biological Process: BMP signaling pathway; positive regulation of hair follicle development; negative regulation of activin receptor signaling pathway; negative regulation of cell differentiation; hair follicle morphogenesis; gamete generation; hemopoietic progenitor cell differentiation; keratinocyte proliferation; negative regulation of transcription from RNA polymerase II promoter; pattern specification process; skeletal development; female gonad development; odontogenesis of dentine-containing teeth Disease: Polycystic Ovary Syndrome 1 |
NCBI Summary: | Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008] |
UniProt Code: | P19883 |
NCBI GenInfo Identifier: | 23831079 |
NCBI Gene ID: | 10468 |
NCBI Accession: | P19883.2 |
UniProt Secondary Accession: | P19883,Q9BTH0, B5BU94, |
UniProt Related Accession: | P19883 |
Molecular Weight: | 34,803 Da |
NCBI Full Name: | Follistatin |
NCBI Synonym Full Names: | follistatin |
NCBI Official Symbol: | FST |
NCBI Official Synonym Symbols: | FS |
NCBI Protein Information: | follistatin; activin-binding protein; follistatin isoform FST317 |
UniProt Protein Name: | Follistatin |
UniProt Synonym Protein Names: | Activin-binding protein |
Protein Family: | Follistatin |
UniProt Gene Name: | FST |
UniProt Entry Name: | FST_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |