FPR1 Antibody (PACO03719)
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주문- SKU:
- PACO03719
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FPR1 Antibody |
Antibody SKU: | PACO03719 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human FPR1. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | FPR1; fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor |
UniProt Protein Function: | FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Motility/polarity/chemotaxis; Receptor, GPCRChromosomal Location of Human Ortholog: 19q13.4Cellular Component: endosome; plasma membraneMolecular Function: N-formyl peptide receptor activity; protein binding; receptor activityBiological Process: activation of MAPK activity; cell motility; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); nitric oxide mediated signal transduction; signal transduction |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] |
UniProt Code: | P21462 |
NCBI GenInfo Identifier: | 288558848 |
NCBI Gene ID: | 2357 |
NCBI Accession: | P21462.3 |
UniProt Secondary Accession: | P21462,Q14939, Q7Z6A4, Q86U52, Q9NS48 |
UniProt Related Accession: | P21462 |
Molecular Weight: | 38,446 Da |
NCBI Full Name: | fMet-Leu-Phe receptor |
NCBI Synonym Full Names: | formyl peptide receptor 1 |
NCBI Official Symbol: | FPR1 |
NCBI Official Synonym Symbols: | FPR; FMLP |
NCBI Protein Information: | fMet-Leu-Phe receptor |
UniProt Protein Name: | fMet-Leu-Phe receptor |
UniProt Synonym Protein Names: | N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor |
Protein Family: | FK506-binding protein |
UniProt Gene Name: | FPR1 |
UniProt Entry Name: | FPR1_HUMAN |