FOXB1 Antibody (PACO17879)
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주문- SKU:
- PACO17879
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FOXB1 Antibody (PACO17879) |
Antibody SKU: | PACO17879 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human FOXB1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17879(FOXB1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17879(FOXB1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function. |
Synonyms: | forkhead box B1 |
UniProt Protein Function: | FOXB1: |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding Biological Process: lactation; transcription from RNA polymerase II promoter; floor plate development; somitogenesis; thalamus development; regulation of transcription from RNA polymerase II promoter; axon target recognition; spinal cord development; mammilary body development; midbrain development; visual learning; negative regulation of neuron apoptosis; hypothalamus cell migration; urogenital system development; telencephalon cell migration |
UniProt Code: | Q99853 |
NCBI GenInfo Identifier: | 215274160 |
NCBI Gene ID: | 27023 |
NCBI Accession: | Q99853.3 |
UniProt Secondary Accession: | Q99853,O60652, O75917, Q14CL2, |
UniProt Related Accession: | Q99853 |
Molecular Weight: | 34,978 Da |
NCBI Full Name: | Forkhead box protein B1 |
NCBI Synonym Full Names: | forkhead box B1 |
NCBI Official Symbol: | FOXB1 |
NCBI Official Synonym Symbols: | FKH5; HFKH-5 |
NCBI Protein Information: | forkhead box protein B1; transcription factor FKH-5 |
UniProt Protein Name: | Forkhead box protein B1 |
UniProt Synonym Protein Names: | Transcription factor FKH-5 |
Protein Family: | Forkhead box protein |
UniProt Gene Name: | FOXB1 |
UniProt Entry Name: | FOXB1_HUMAN |
Antibodies |
Anti-FOXB1 Antibody (CAB15152) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |