FMNL1 Antibody (PACO16367)
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주문- SKU:
- PACO16367
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FMNL1 Antibody (PACO16367) |
Antibody SKU: | PACO16367 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:20-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human FMNL1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A172 cells, Primary antibody: PACO16367(FMNL1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO16367(FMNL1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. |
Synonyms: | formin-like 1 |
UniProt Protein Function: | FMNL1: May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q21 Cellular Component: membrane; plasma membrane; phagocytic vesicle; cell cortex; cytosol Molecular Function:actin filament binding; protein binding; Rac GTPase binding; GTPase activating protein binding; profilin binding Biological Process: substrate-bound cell migration; regulation of cell shape; actin filament severing; cortical actin cytoskeleton organization and biogenesis |
UniProt Code: | O95466 |
NCBI GenInfo Identifier: | 1519314519 |
NCBI Gene ID: | |
NCBI Accession: | NP_005883 |
Molecular Weight: | 122kDa |
NCBI Full Name: | formin-like protein 1 |
UniProt Protein Name: | Formin-like protein 1 |
UniProt Synonym Protein Names: | CLL-associated antigen KW-13; Leukocyte formin |
UniProt Gene Name: | FMNL1 |
UniProt Entry Name: | FMNL_HUMAN |