FGF12 Antibody (PACO01875)
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주문- SKU:
- PACO01875
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FGF12 Antibody |
Antibody SKU: | PACO01875 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the Internal region of human FGF-12. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | FGF12; FGF12B; FHF1; Fibroblast growth factor 12; FGF-12; Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor |
UniProt Protein Function: | FGF12: Probably involved in nervous system development and function. Belongs to the heparin-binding growth factors family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Cytokine Chromosomal Location of Human Ortholog: 3q28 Cellular Component: extracellular space; intracellular; nucleus Molecular Function:fibroblast growth factor receptor binding; growth factor activity; heparin binding; protein binding; sodium channel regulator activity Biological Process: adult locomotory behavior; cell-cell signaling; fibroblast growth factor receptor signaling pathway; heart development; JNK cascade; nervous system development; neuromuscular process; signal transduction; synaptic transmission |
NCBI Summary: | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | P61328 |
NCBI GenInfo Identifier: | 47117683 |
NCBI Gene ID: | 2257 |
NCBI Accession: | P61328.1 |
UniProt Secondary Accession: | P61328,O35339, P70376, Q8TBG5, Q92912, Q93001, B2R6B7 B2R976, |
UniProt Related Accession: | P61328 |
Molecular Weight: | 20,424 Da |
NCBI Full Name: | Fibroblast growth factor 12 |
NCBI Synonym Full Names: | fibroblast growth factor 12 |
NCBI Official Symbol: | FGF12 |
NCBI Official Synonym Symbols: | FHF1; FGF12B |
NCBI Protein Information: | fibroblast growth factor 12 |
UniProt Protein Name: | Fibroblast growth factor 12 |
UniProt Synonym Protein Names: | Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor |
Protein Family: | Fibroblast growth factor |
UniProt Gene Name: | FGF12 |
UniProt Entry Name: | FGF12_HUMAN |