FABP6 Antibody (PACO42971)
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주문- SKU:
- PACO42971
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FABP6 Antibody (PACO42971) |
Antibody SKU: | PACO42971 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Gastrotropin protein (1-128AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Gastrotropin antibody at 8µg/ml. Lane 1: Mouse small intestine tissue. Lane 2: Rat small intestine tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 15, 20 kDa. Observed band size: 15 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO42971 at dilution of 1:100. |
Background: | Ileal protein which stimulates gastric acid, and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid, induced apoptosis. |
Synonyms: | Gastrotropin (GT) (Fatty acid, binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid, binding protein) (I-BABP), FABP6, ILBP ILLBP |
UniProt Protein Function: | FABP6: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. 2 isoforms of the human protein are produced by alternative promoter. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 5q33.3-q34 Cellular Component: cytoplasm; cytosol Molecular Function:transporter activity; lipid binding Biological Process: bile acid and bile salt transport; negative regulation of cell proliferation; bile acid metabolic process; lipid metabolic process; transmembrane transport |
NCBI Summary: | This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51161 |
NCBI GenInfo Identifier: | 1708457 |
NCBI Gene ID: | 2172 |
NCBI Accession: | P51161.2 |
UniProt Secondary Accession: | P51161,Q07DR7, Q8TBI3, Q9UGI7, |
UniProt Related Accession: | P51161 |
Molecular Weight: | 128 |
NCBI Full Name: | Gastrotropin |
NCBI Synonym Full Names: | fatty acid binding protein 6, ileal |
NCBI Official Symbol: | FABP6 |
NCBI Official Synonym Symbols: | ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB |
NCBI Protein Information: | gastrotropin; GT; intestinal 15 kDa protein; ileal lipid-binding protein; illeal lipid-binding protein; ileal bile acid binding protein |
UniProt Protein Name: | Gastrotropin |
UniProt Synonym Protein Names: | Fatty acid-binding protein 6; Ileal lipid-binding protein; ILBP; Intestinal 15 kDa protein; I-15P; Intestinal bile acid-binding protein; I-BABP |
Protein Family: | Gastrotropin |
UniProt Gene Name: | FABP6 |
UniProt Entry Name: | FABP6_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |