FABP3 Antibody (PACO17562)
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주문- SKU:
- PACO17562
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | FABP3 Antibody (PACO17562) |
Antibody SKU: | PACO17562 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Synthetic peptide of human FABP3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17562(FABP3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17562(FABP3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The intracellular fatty acid, binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acid, . They may also be responsible in the modulation of cell growth and proliferation. Fatty acid, binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. |
Synonyms: | fatty acid, binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
UniProt Protein Function: | FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 1p33-p32 Cellular Component: extracellular space; sarcoplasm; cytosol Molecular Function:protein binding; icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity Biological Process: response to drug; negative regulation of cell proliferation; cholesterol homeostasis; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis |
NCBI Summary: | The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
UniProt Code: | P05413 |
NCBI GenInfo Identifier: | 119802 |
NCBI Gene ID: | 2170 |
NCBI Accession: | P05413.4 |
UniProt Related Accession: | P05413 |
Molecular Weight: | 14858 |
NCBI Full Name: | Fatty acid-binding protein, heart |
NCBI Synonym Full Names: | fatty acid binding protein 3 |
NCBI Official Symbol: | FABP3 |
NCBI Official Synonym Symbols: | MDGI; FABP11; H-FABP; M-FABP; O-FABP |
NCBI Protein Information: | fatty acid-binding protein, heart |
UniProt Protein Name: | Fatty acid-binding protein, heart |
UniProt Synonym Protein Names: | Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP |
Protein Family: | Fatty acid-binding protein |
UniProt Gene Name: | FABP3 |
UniProt Entry Name: | FABPH_HUMAN |
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