EXTL3 Antibody (PACO31612)
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주문- SKU:
- PACO31612
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EXTL3 Antibody (PACO31612) |
Antibody SKU: | PACO31612 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Exostosin-like 3 protein (2-245AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: EXTL3 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted bane side: 105 kDa Observed band side: 105 kDa . |
![]() | Immunofluorescent analysis of Hela cells using PACO31612 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO31612 at dilution of 1:100. |
Background: | Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. |
Synonyms: | Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3), EXTL3, EXTL1L EXTR1 KIAA0519 |
UniProt Protein Function: | EXTL3: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transferase; EC 2.4.1.223; Glycan Metabolism - heparan sulfate biosynthesis Chromosomal Location of Human Ortholog: 8p21 Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane Molecular Function:metal ion binding; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity Biological Process: glycosaminoglycan biosynthetic process; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; unfolded protein response; heparan sulfate proteoglycan biosynthetic process; positive regulation of cell growth |
NCBI Summary: | This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012] |
UniProt Code: | O43909 |
NCBI GenInfo Identifier: | 6166159 |
NCBI Gene ID: | 2137 |
NCBI Accession: | O43909.1 |
UniProt Secondary Accession: | O43909,O00225, Q53XT3, D3DST8, |
UniProt Related Accession: | O43909 |
Molecular Weight: | Observed MW 105kDaCalculated MW 104kDa |
NCBI Full Name: | Exostosin-like 3 |
NCBI Synonym Full Names: | exostosin-like glycosyltransferase 3 |
NCBI Official Symbol: | EXTL3 |
NCBI Official Synonym Symbols: | RPR; BOTV; REGR; EXTR1; EXTL1L |
NCBI Protein Information: | exostosin-like 3; reg receptor; EXT-related 1; exostosin tumor-like 3; exostoses (multiple)-like 3; putative tumor suppressor protein EXTL3; hereditary multiple exostoses gene isolog; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase |
UniProt Protein Name: | Exostosin-like 3 |
UniProt Synonym Protein Names: | EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3 |
Protein Family: | Exostosin |
UniProt Gene Name: | EXTL3 |
UniProt Entry Name: | EXTL3_HUMAN |
Antibodies | ELISA Kits |
Anti-EXTL3 Antibody (CAB3857) | Human EXTL3 (Exostosin-like 3) ELISA Kit (HUFI04361) |
EXTL3 Antibody (PACO09176) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |