ENTPD2 Antibody (PACO44284)
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주문- SKU:
- PACO44284
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ENTPD2 Antibody (PACO44284) |
Antibody SKU: | PACO44284 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 2 protein (28-268AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: ENTPD2antibody at 3.6µg/ml. Lane 1: Human placenta tissue. Lane 2: U87 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 54, 52, 49 kDa. Observed band size: 54 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO44284 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO44284 at dilution of 1:100. |
Background: | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. |
Synonyms: | Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2), ENTPD2, CD39L1 |
UniProt Protein Function: | ENTPD2: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.6.1.-; Nucleotide Metabolism - purine; Extracellular matrix; Membrane protein, integral; Membrane protein, multi-pass; Hydrolase Chromosomal Location of Human Ortholog: 9q34 Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; basal lamina Molecular Function:nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; purine ribonucleoside diphosphate catabolic process |
NCBI Summary: | The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y5L3 |
NCBI GenInfo Identifier: | 18203633 |
NCBI Gene ID: | 954 |
NCBI Accession: | Q9Y5L3.1 |
UniProt Secondary Accession: | Q9Y5L3,O15464, Q5SPY6, Q5SPY7, |
UniProt Related Accession: | Q9Y5L3 |
Molecular Weight: | 495 |
NCBI Full Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
NCBI Synonym Full Names: | ectonucleoside triphosphate diphosphohydrolase 2 |
NCBI Official Symbol: | ENTPD2 |
NCBI Official Synonym Symbols: | CD39L1; NTPDase-2 |
NCBI Protein Information: | ectonucleoside triphosphate diphosphohydrolase 2; NTPDase 2; ecto-ATPase 2; ecto-ATPDase 2; CD39 antigen-like 1; ecto-ATP diphosphohydrolase 2 |
UniProt Protein Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
UniProt Synonym Protein Names: | CD39 antigen-like 1; Ecto-ATP diphosphohydrolase 2; Ecto-ATPDase 2; Ecto-ATPase 2 |
Protein Family: | Ectonucleoside triphosphate diphosphohydrolase |
UniProt Gene Name: | ENTPD2 |
UniProt Entry Name: | ENTP2_HUMAN |
Antibodies |
Anti-ENTPD2 Antibody (CAB6584) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |