ENPP7 Antibody (PACO63135)
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주문- SKU:
- PACO63135
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ENPP7 Antibody (PACO63135) |
Antibody SKU: | PACO63135 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:200-1:500 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 protein (22-216AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: K562 whole cell lysate, HeLa whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, Mouse heart tissue, Mouse kidney tissue. All lanes: ENPP7 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa. |
![]() | Immunofluorescence staining of HepG2 cells with PACO63135 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. |
Synonyms: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase), ENPP7 |
UniProt Protein Function: | ENPP7: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
UniProt Protein Details: | Protein type:Phosphodiesterase; Lipid Metabolism - sphingolipid; Cell cycle regulation; DNA replication; Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.4.12 Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: Golgi apparatus; microvillus; membrane; integral to membrane; plasma membrane Molecular Function:sphingomyelin phosphodiesterase activity Biological Process: negative regulation of cell proliferation; sphingomyelin metabolic process; sphingolipid metabolic process; negative regulation of DNA replication; glycosphingolipid metabolic process; sphingomyelin catabolic process |
UniProt Code: | Q6UWV6 |
NCBI GenInfo Identifier: | 134047772 |
NCBI Gene ID: | 339221 |
NCBI Accession: | Q6UWV6.3 |
UniProt Secondary Accession: | Q6UWV6,Q6ZTS5, Q8IUS8, |
UniProt Related Accession: | Q6UWV6 |
Molecular Weight: | 458 |
NCBI Full Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
NCBI Synonym Full Names: | ectonucleotide pyrophosphatase/phosphodiesterase 7 |
NCBI Official Symbol: | ENPP7 |
NCBI Official Synonym Symbols: | NPP7; NPP-7; E-NPP 7; ALK-SMase |
NCBI Protein Information: | ectonucleotide pyrophosphatase/phosphodiesterase family member 7; ENPP7; alkaline sphingomyelinase; intestinal alkaline sphingomyelinase; alkaline sphingomyelin phosphodiesterase |
UniProt Protein Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
UniProt Synonym Protein Names: | Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase; Alk-SMase |
Protein Family: | Ectonucleotide pyrophosphatase/phosphodiesterase family |
UniProt Gene Name: | ENPP7 |
UniProt Entry Name: | ENPP7_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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