ENPP7 Antibody (PACO17830)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO17830
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ENPP7 Antibody (PACO17830) |
Antibody SKU: | PACO17830 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Synthetic peptide of human ENPP7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: 293T cells, Primary antibody: PACO17830(ENPP7 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17830(ENPP7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) also known as alkaline sphingomyelin phosphodiesterase (Alk-SMase) or intestinal alkaline sphingomyelinase is an enzyme that in humans is encoded by the ENPP7 gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon. |
Synonyms: | ectonucleotide pyrophosphatase/phosphodiesterase 7 |
UniProt Protein Function: | ENPP7: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
UniProt Protein Details: | Protein type:Phosphodiesterase; Lipid Metabolism - sphingolipid; Cell cycle regulation; DNA replication; Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.1.4.12 Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: Golgi apparatus; microvillus; membrane; integral to membrane; plasma membrane Molecular Function:sphingomyelin phosphodiesterase activity Biological Process: negative regulation of cell proliferation; sphingomyelin metabolic process; sphingolipid metabolic process; negative regulation of DNA replication; glycosphingolipid metabolic process; sphingomyelin catabolic process |
UniProt Code: | Q6UWV6 |
NCBI GenInfo Identifier: | 134047772 |
NCBI Gene ID: | 339221 |
NCBI Accession: | Q6UWV6.3 |
UniProt Secondary Accession: | Q6UWV6,Q6ZTS5, Q8IUS8, |
UniProt Related Accession: | Q6UWV6 |
Molecular Weight: | 458 |
NCBI Full Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
NCBI Synonym Full Names: | ectonucleotide pyrophosphatase/phosphodiesterase 7 |
NCBI Official Symbol: | ENPP7 |
NCBI Official Synonym Symbols: | NPP7; NPP-7; E-NPP 7; ALK-SMase |
NCBI Protein Information: | ectonucleotide pyrophosphatase/phosphodiesterase family member 7; ENPP7; alkaline sphingomyelinase; intestinal alkaline sphingomyelinase; alkaline sphingomyelin phosphodiesterase |
UniProt Protein Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
UniProt Synonym Protein Names: | Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase; Alk-SMase |
Protein Family: | Ectonucleotide pyrophosphatase/phosphodiesterase family |
UniProt Gene Name: | ENPP7 |
UniProt Entry Name: | ENPP7_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |