ENDOG Antibody (PACO19601)
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주문- SKU:
- PACO19601
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ENDOG Antibody (PACO19601) |
Antibody SKU: | PACO19601 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human ENDOG |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19601(ENDOG Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19601(ENDOG Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase γ to initiate replication of mitochondrial DNA. |
Synonyms: | endonuclease G |
UniProt Protein Function: | ENDOG: Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. Homodimer. Belongs to the DNA/RNA non-specific endonuclease family. |
UniProt Protein Details: | Protein type:EC 3.1.30.-; Ribonuclease; Deoxyribonuclease; Apoptosis; Mitochondrial Chromosomal Location of Human Ortholog: 9q34.1 Cellular Component: mitochondrion Molecular Function:protein binding; nuclease activity; nucleic acid binding; metal ion binding; endonuclease activity Biological Process: response to antibiotic; positive regulation of apoptosis; in utero embryonic development; DNA fragmentation during apoptosis; DNA recombination |
NCBI Summary: | The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14249 |
NCBI GenInfo Identifier: | 24638471 |
NCBI Gene ID: | 2021 |
NCBI Accession: | Q14249.3 |
UniProt Secondary Accession: | Q14249,Q5T281, Q9BSP2, |
UniProt Related Accession: | Q14249 |
Molecular Weight: | 32,620 Da |
NCBI Full Name: | Endonuclease G, mitochondrial |
NCBI Synonym Full Names: | endonuclease G |
NCBI Official Symbol: | ENDOG |
NCBI Protein Information: | endonuclease G, mitochondrial; endo G; mitochondrial endonuclease G |
UniProt Protein Name: | Endonuclease G, mitochondrial |
Protein Family: | Endoglin |
UniProt Gene Name: | ENDOG |
UniProt Entry Name: | NUCG_HUMAN |
Antibodies | ELISA Kits |
Anti-Endo G Antibody (CAB0604) | Human ENDOG (Endonuclease G) ELISA Kit (HUFI07945) |
Anti-Endo G Antibody (CAB8801) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |