EIF5 Antibody (PACO16242)
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주문- SKU:
- PACO16242
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EIF5 Antibody (PACO16242) |
Antibody SKU: | PACO16242 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human EIF5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16242(EIF5 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16242(EIF5 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations |
Synonyms: | eukaryotic translation initiation factor 5 |
UniProt Protein Function: | EIF5: eukaryotic translation initiation factor 5. Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex. |
UniProt Protein Details: | Protein type:Translation initiation; Translation Chromosomal Location of Human Ortholog: 14q32.32 Cellular Component: cytoplasm; cytosol; nucleus; plasma membrane Molecular Function:GTPase activity; protein binding; translation factor activity, nucleic acid binding Biological Process: regulation of translational initiation |
NCBI Summary: | Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010] |
UniProt Code: | P55010 |
NCBI GenInfo Identifier: | 27735202 |
NCBI Gene ID: | 1983 |
NCBI Accession: | P55010.2 |
UniProt Secondary Accession: | P55010,Q53XB3, Q9H5N2, Q9UG48, |
UniProt Related Accession: | P55010 |
Molecular Weight: | 49,223 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 5 |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 5 |
NCBI Official Symbol: | EIF5 |
NCBI Official Synonym Symbols: | EIF-5; EIF-5A |
NCBI Protein Information: | eukaryotic translation initiation factor 5 |
UniProt Protein Name: | Eukaryotic translation initiation factor 5 |
UniProt Gene Name: | EIF5 |
UniProt Entry Name: | IF5_HUMAN |