EIF4B Antibody (PACO49554)
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주문- SKU:
- PACO49554
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | EIF4B Antibody (PACO49554) |
Antibody SKU: | PACO49554 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Eukaryotic translation initiation factor 4B protein (362-590AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO49554 at dilution of 1:100. | |
Immunofluorescent analysis of Hela cells using PACO49554 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human skin tissue using PACO49554 at dilution of 1:100. |
Background: | Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
Synonyms: | Eukaryotic translation initiation factor 4B (eIF-4B), EIF4B |
UniProt Protein Function: | EIF4B: eukaryotic translation initiation factor 4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
UniProt Protein Details: | Protein type:RNA-binding; Translation initiation; Translation Chromosomal Location of Human Ortholog: 12q13.13 Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; polysome Molecular Function:helicase activity; protein binding; ribosomal small subunit binding; RNA binding; RNA strand annealing activity; RNA strand-exchange activity Biological Process: formation of translation preinitiation complex; poly(A) tail shortening; regulation of translational initiation; translational initiation |
UniProt Code: | P23588 |
NCBI GenInfo Identifier: | 205371761 |
NCBI Gene ID: | 1975 |
NCBI Accession: | P23588.2 |
UniProt Secondary Accession: | P23588,Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5, B4DS13 |
UniProt Related Accession: | P23588 |
Molecular Weight: | 64,805 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4B |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4B |
NCBI Official Symbol: | EIF4B |
NCBI Official Synonym Symbols: | EIF-4B; PRO1843 |
NCBI Protein Information: | eukaryotic translation initiation factor 4B |
UniProt Protein Name: | Eukaryotic translation initiation factor 4B |
Protein Family: | Eukaryotic translation initiation factor |
UniProt Gene Name: | EIF4B |
UniProt Entry Name: | IF4B_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |