DUSP22 Antibody (PACO44536)
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주문- SKU:
- PACO44536
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DUSP22 Antibody (PACO44536) |
Antibody SKU: | PACO44536 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dual specificity protein phosphatase 22 protein (1-184AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO44536 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human heart tissue using PACO44536 at dilution of 1:100. |
Background: | Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity). |
Synonyms: | Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x), DUSP22, JSP1 LMWDSP2 MKPX |
UniProt Protein Function: | DUSP22: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK). Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.48; EC 3.1.3.16; Apoptosis Chromosomal Location of Human Ortholog: 6p25.3 Cellular Component: cytoplasm; nucleus Molecular Function:protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity Biological Process: cell proliferation; apoptosis; multicellular organismal development; transforming growth factor beta receptor signaling pathway; positive regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter; protein amino acid dephosphorylation; inactivation of MAPK activity; regulation of cell proliferation |
UniProt Code: | Q9NRW4 |
NCBI GenInfo Identifier: | 74752929 |
NCBI Gene ID: | 56940 |
NCBI Accession: | Q9NRW4.1 |
UniProt Secondary Accession: | Q9NRW4,Q59GW2, Q5VWR2, Q96AR1, B4DK56, |
UniProt Related Accession: | Q9NRW4 |
Molecular Weight: | 184 |
NCBI Full Name: | Dual specificity protein phosphatase 22 |
NCBI Synonym Full Names: | dual specificity phosphatase 22 |
NCBI Official Symbol: | DUSP22 |
NCBI Official Synonym Symbols: | VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2 |
NCBI Protein Information: | dual specificity protein phosphatase 22; MAP kinase phosphatase x; JNK-stimulating phosphatase 1; JNK-stimulatory phosphatase-1; mitogen-activated protein kinase phosphatase x; low molecular weight dual specificity phosphatase 2; homolog of mouse dual specificity phosphatase LMW-DSP2 |
UniProt Protein Name: | Dual specificity protein phosphatase 22 |
UniProt Synonym Protein Names: | JNK-stimulatory phosphatase-1; JSP-1; Low molecular weight dual specificity phosphatase 2; LMW-DSP2; Mitogen-activated protein kinase phosphatase x; MAP kinase phosphatase x; MKP-x |
Protein Family: | Dual specificity protein phosphatase |
UniProt Gene Name: | DUSP22 |
UniProt Entry Name: | DUS22_HUMAN |