DNAJC7 Antibody (PACO14817)
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주문- SKU:
- PACO14817
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DNAJC7 Antibody (PACO14817) |
Antibody SKU: | PACO14817 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human DNAJC7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14817(DNAJC7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human seminoma tissue, Primary antibody: PACO14817(DNAJC7 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14817(DNAJC7 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants. |
Synonyms: | DnaJ (Hsp40) homolog, subfamily C, member 7 |
UniProt Protein Function: | DNAJC7: a co-chaperone protein that binds both Hsp70 and Hsp90 through its TPR domains. Its DnaJ domain stimulates ATP hydrolysis and polypeptide binding by Hsp70. Interacts with the proapoptotic and cell-cycle checkpoint protein Rad9. Rad9 transiently dissociates from Tpr2 following heat-shock or UV treatments. |
UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: nucleoplasm; cytoskeleton; membrane; cytoplasm Molecular Function:protein binding; heat shock protein binding Biological Process: protein folding |
NCBI Summary: | This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
UniProt Code: | Q99615 |
NCBI GenInfo Identifier: | 46397879 |
NCBI Gene ID: | 7266 |
NCBI Accession: | Q99615.2 |
UniProt Related Accession: | Q99615 |
Molecular Weight: | 60kDa |
NCBI Full Name: | DnaJ homolog subfamily C member 7 |
NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member C7 |
NCBI Official Symbol: | DNAJC7 |
NCBI Official Synonym Symbols: | DJ11; DJC7; TPR2; TTC2 |
NCBI Protein Information: | dnaJ homolog subfamily C member 7 |
UniProt Protein Name: | DnaJ homolog subfamily C member 7 |
UniProt Synonym Protein Names: | Tetratricopeptide repeat protein 2; TPR repeat protein 2 |
Protein Family: | DnaJ homolog subfamily |
UniProt Gene Name: | DNAJC7 |
UniProt Entry Name: | DNJC7_HUMAN |