DLGAP2 Antibody (PACO59461)
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주문- SKU:
- PACO59461
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DLGAP2 Antibody (PACO59461) |
Antibody SKU: | PACO59461 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Disks large-associated protein 2 protein (31-139AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunofluorescence staining of HepG2 cells with PACO59461 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. |
Synonyms: | Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2), DLGAP2, C8orf68 DAP2 ERICH1-AS1 |
UniProt Protein Function: | SAPAP2: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Kinase, other Chromosomal Location of Human Ortholog: 8p23 Cellular Component: postsynaptic membrane; postsynaptic density; neurofilament; cell junction Molecular Function:protein binding Biological Process: nerve-nerve synaptic transmission |
NCBI Summary: | The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014] |
UniProt Code: | Q9P1A6 |
NCBI GenInfo Identifier: | 160395585 |
NCBI Gene ID: | 9228 |
NCBI Accession: | Q9P1A6.4 |
UniProt Secondary Accession: | Q9P1A6,O14488, O14664, Q9P1A7, A1QCF8, A1QCF9, A5D8Y2 |
UniProt Related Accession: | Q9P1A6 |
Molecular Weight: | |
NCBI Full Name: | Disks large-associated protein 2 |
NCBI Synonym Full Names: | discs, large (Drosophila) homolog-associated protein 2 |
NCBI Official Symbol: | DLGAP2 |
NCBI Official Synonym Symbols: | DAP2; SAPAP2 |
NCBI Protein Information: | disks large-associated protein 2; PSD-95/SAP90-binding protein 2; discs large-associated protein 2; SAP90/PSD-95-associated protein 2 |
UniProt Protein Name: | Disks large-associated protein 2 |
UniProt Synonym Protein Names: | PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2 |
Protein Family: | Disks large-associated protein |
UniProt Gene Name: | DLGAP2 |
UniProt Entry Name: | DLGP2_HUMAN |
Antibodies |
Anti-DLGAP2 Antibody (CAB13818) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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