DHX8 Antibody (PACO00697)
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주문- SKU:
- PACO00697
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DHX8 Antibody |
Antibody SKU: | PACO00697 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human DDX8. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | DHX8; DDX8; ATP-dependent RNA helicase DHX8; DEAH box protein 8; RNA helicase HRH1 |
UniProt Protein Function: | DDX8: Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily. |
UniProt Protein Details: | Protein type:Spliceosome; EC 3.6.4.13; RNA processing; RNA splicing; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: nucleoplasm; spliceosome; cytoplasm; nucleus Molecular Function:identical protein binding; protein binding; ATP-dependent RNA helicase activity; ATP binding Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing |
NCBI Summary: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14562 |
NCBI GenInfo Identifier: | 4826690 |
NCBI Gene ID: | 1659 |
NCBI Accession: | NP_004932.1 |
UniProt Related Accession: | Q14562 |
Molecular Weight: | 139,315 Da |
NCBI Full Name: | ATP-dependent RNA helicase DHX8 |
NCBI Synonym Full Names: | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
NCBI Official Symbol: | DHX8 |
NCBI Official Synonym Symbols: | DDX8; HRH1; PRP22; PRPF22 |
NCBI Protein Information: | ATP-dependent RNA helicase DHX8; RNA helicase HRH1; DEAH box protein 8; DEAH-box protein 8; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase) |
UniProt Protein Name: | ATP-dependent RNA helicase DHX8 |
UniProt Synonym Protein Names: | DEAH box protein 8; RNA helicase HRH1 |
Protein Family: | ATP-dependent RNA helicase |
UniProt Gene Name: | DHX8 |
UniProt Entry Name: | DHX8_HUMAN |