DGKE Antibody (PACO43727)
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주문- SKU:
- PACO43727
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DGKE Antibody (PACO43727) |
Antibody SKU: | PACO43727 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Diacylglycerol kinase epsilon protein (40-260AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: Diacylglycerol kinase epsilon antibody at 5µg/ml Lane 1: Rat brain tissue Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 64, 21 kDa Observed band size: 64 kDa |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43727 at dilution of 1:100 |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO43727 at dilution of 1:100 |
Background: | Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid, composition. |
Synonyms: | Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon), DGKE, DAGK5 |
UniProt Protein Function: | DGKE: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. Belongs to the eukaryotic diacylglycerol kinase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.7.1.107; Motility/polarity/chemotaxis; Kinase, lipid Chromosomal Location of Human Ortholog: 17q22 Cellular Component: membrane; cytoplasm; integral to membrane; plasma membrane Molecular Function:metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; phospholipid biosynthetic process Disease: Nephrotic Syndrome, Type 7 |
NCBI Summary: | Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52429 |
NCBI GenInfo Identifier: | 4503313 |
NCBI Gene ID: | 8526 |
NCBI Accession: | NP_003638.1 |
UniProt Related Accession: | P52429 |
Molecular Weight: | ~ 64kDa |
NCBI Full Name: | diacylglycerol kinase epsilon |
NCBI Synonym Full Names: | diacylglycerol kinase epsilon |
NCBI Official Symbol: | DGKE |
NCBI Official Synonym Symbols: | DGK; AHUS7; DAGK5; DAGK6; NPHS7 |
NCBI Protein Information: | diacylglycerol kinase epsilon |
UniProt Protein Name: | Diacylglycerol kinase epsilon |
UniProt Synonym Protein Names: | Diglyceride kinase epsilon |
Protein Family: | Deoxyguanosine kinase |
UniProt Gene Name: | DGKE |
UniProt Entry Name: | DGKE_HUMAN |