DGKE Antibody (PACO21798)
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주문- SKU:
- PACO21798
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DGKE Antibody (PACO21798) |
Antibody SKU: | PACO21798 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human DGKE. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Sjoeblom T., Science 314:268-274(2006). |
Clonality: | Polyclonal |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from K562 cells, using DGKE antibody. |
Synonyms: | Diacylglycerol kinase epsilon; EC 2.7.1.107; Diglyceride kinase epsilon; DGK-epsilon; DAG kinase epsilon |
UniProt Protein Function: | DGKE: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. Belongs to the eukaryotic diacylglycerol kinase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.7.1.107; Motility/polarity/chemotaxis; Kinase, lipid Chromosomal Location of Human Ortholog: 17q22 Cellular Component: membrane; cytoplasm; integral to membrane; plasma membrane Molecular Function:metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; phospholipid biosynthetic process Disease: Nephrotic Syndrome, Type 7 |
NCBI Summary: | Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52429 |
NCBI GenInfo Identifier: | 4503313 |
NCBI Gene ID: | 8526 |
NCBI Accession: | NP_003638.1 |
UniProt Related Accession: | P52429 |
Molecular Weight: | ~ 64kDa |
NCBI Full Name: | diacylglycerol kinase epsilon |
NCBI Synonym Full Names: | diacylglycerol kinase epsilon |
NCBI Official Symbol: | DGKE |
NCBI Official Synonym Symbols: | DGK; AHUS7; DAGK5; DAGK6; NPHS7 |
NCBI Protein Information: | diacylglycerol kinase epsilon |
UniProt Protein Name: | Diacylglycerol kinase epsilon |
UniProt Synonym Protein Names: | Diglyceride kinase epsilon |
Protein Family: | Deoxyguanosine kinase |
UniProt Gene Name: | DGKE |
UniProt Entry Name: | DGKE_HUMAN |
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