DES Antibody (PACO08807)
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주문- SKU:
- PACO08807
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | DES Antibody (PACO08807) |
Antibody SKU: | PACO08807 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human DES |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | desmin;DES;CMD1I;CSM1;CSM2;FLJ12025;FLJ39719;FLJ41013;FLJ41793 ; |
UniProt Protein Function: | desmin: a class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 2q35 Cellular Component: intermediate filament; fascia adherens; cytosol; neuromuscular junction; Z disc; sarcolemma Molecular Function:identical protein binding; protein binding; structural constituent of cytoskeleton; cytoskeletal protein binding Biological Process: muscle contraction; cytoskeleton organization and biogenesis; regulation of heart contraction; muscle filament sliding Disease: Cardiomyopathy, Dilated, 1i; Scapuloperoneal Syndrome, Neurogenic, Kaeser Type; Myopathy, Myofibrillar, 1; Muscular Dystrophy, Limb-girdle, Type 2r |
NCBI Summary: | This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008] |
UniProt Code: | P17661 |
NCBI GenInfo Identifier: | 6686280 |
NCBI Gene ID: | 1674 |
NCBI Accession: | P17661.3 |
UniProt Secondary Accession: | P17661,Q15787, Q549R7, Q549R8, Q549R9, Q8IZR1, Q8IZR6 Q8NES2, Q8NEU6, Q8TAC4, Q8TCX2, Q8TD99, |
UniProt Related Accession: | P17661 |
Molecular Weight: | |
NCBI Full Name: | Desmin |
NCBI Synonym Full Names: | desmin |
NCBI Official Symbol: | DES |
NCBI Official Synonym Symbols: | CSM1; CSM2; LGMD2R |
NCBI Protein Information: | desmin; mutant desmin p.K241E; intermediate filament protein |
UniProt Protein Name: | Desmin |
Protein Family: | Desmin |
UniProt Gene Name: | DES |
UniProt Entry Name: | DESM_HUMAN |