CSF2RB Antibody (PACO19722)
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주문- SKU:
- PACO19722
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CSF2RB Antibody (PACO19722) |
Antibody SKU: | PACO19722 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human CSF2RB |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19722(CSF2RB Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19722(CSF2RB Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is the common β chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). |
Synonyms: | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
UniProt Protein Function: | CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane Molecular Function:interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5 |
NCBI Summary: | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008] |
UniProt Code: | P32927 |
NCBI GenInfo Identifier: | 1345923 |
NCBI Gene ID: | 1439 |
NCBI Accession: | P32927.2 |
UniProt Secondary Accession: | P32927,Q5JZI1, Q6ICE0, |
UniProt Related Accession: | P32927 |
Molecular Weight: | 97,976 Da |
NCBI Full Name: | Cytokine receptor common subunit beta |
NCBI Synonym Full Names: | colony stimulating factor 2 receptor beta common subunit |
NCBI Official Symbol: | CSF2RB |
NCBI Official Synonym Symbols: | CD131; IL3RB; IL5RB; SMDP5; CDw131 |
NCBI Protein Information: | cytokine receptor common subunit beta |
UniProt Protein Name: | Cytokine receptor common subunit beta |
UniProt Synonym Protein Names: | CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131 |
Protein Family: | Cytokine receptor |
UniProt Gene Name: | CSF2RB |
UniProt Entry Name: | IL3RB_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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