CPM Antibody (PACO22239)
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주문- SKU:
- PACO22239
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CPM Antibody (PACO22239) |
Antibody SKU: | PACO22239 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CPM. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from A549 cells, using CPM antibody. |
Background: | Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. |
Synonyms: | Carboxypeptidase M; EC 3.4.17.12; CPM; |
UniProt Protein Function: | CPM: Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. Belongs to the peptidase M14 family. |
UniProt Protein Details: | Protein type:EC 3.4.17.12; Protease; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 12q14.3 Cellular Component: cell surface; plasma membrane Molecular Function:carboxypeptidase activity; zinc ion binding; metallocarboxypeptidase activity Biological Process: anatomical structure morphogenesis; proteolysis |
NCBI Summary: | The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P14384 |
NCBI GenInfo Identifier: | 14916957 |
NCBI Gene ID: | 1368 |
NCBI Accession: | P14384.2 |
UniProt Secondary Accession: | P14384,Q9H2K9, B2R800, |
UniProt Related Accession: | P14384 |
Molecular Weight: | 443 |
NCBI Full Name: | Carboxypeptidase M |
NCBI Synonym Full Names: | carboxypeptidase M |
NCBI Official Symbol: | CPM |
NCBI Protein Information: | carboxypeptidase M; renal carboxypeptidase; urinary carboxypeptidase B |
UniProt Protein Name: | Carboxypeptidase M |
Protein Family: | Carboxypeptidase |
UniProt Gene Name: | CPM |
UniProt Entry Name: | CBPM_HUMAN |
Antibodies | ELISA Kits |
Anti-CPM Antibody (CAB6565) | Human Carboxypeptidase M / CPM ELISA Kit |
CPM Antibody (PACO00634) | Human Carboxypeptidase M (CPM) ELISA Kit |
CPM Antibody (PACO08569) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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