CPLX2 Antibody (PACO43625)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO43625
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CPLX2 Antibody (PACO43625) |
Antibody SKU: | PACO43625 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Complexin-2 protein (1-134AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Complexin-2 antibody at 6µg/ml. Lane 1: Rat brain tissue. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 15 kDa. Observed band size: 15 kDa. |
Background: | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). |
Synonyms: | Complexin-2 (Complexin II) (CPX II) (Synaphin-1), CPLX2 |
UniProt Protein Function: | CPLX2: Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis. Belongs to the complexin/synaphin family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 5q35.2 Cellular Component: mast cell granule; cell soma; dendrite; synapse; cytosol Molecular Function:syntaxin-1 binding; calcium-dependent protein binding Biological Process: regulation of exocytosis; nervous system development; synaptic vesicle exocytosis; positive regulation of synaptic plasticity; mast cell degranulation; cell differentiation; vesicle docking during exocytosis |
NCBI Summary: | Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6PUV4 |
NCBI GenInfo Identifier: | 51316998 |
NCBI Gene ID: | 10814 |
NCBI Accession: | Q6PUV4.2 |
UniProt Secondary Accession: | Q6PUV4,O09056, Q13329, Q28184, Q52M15, Q64386, B2RAG2 |
UniProt Related Accession: | Q6PUV4 |
Molecular Weight: | 15,394 Da |
NCBI Full Name: | Complexin-2 |
NCBI Synonym Full Names: | complexin 2 |
NCBI Official Symbol: | CPLX2 |
NCBI Official Synonym Symbols: | CPX2; Hfb1; 921-L; CPX-2 |
NCBI Protein Information: | complexin-2; CPX II; complexin II; synaphin 1; synaphin-1 |
UniProt Protein Name: | Complexin-2 |
UniProt Synonym Protein Names: | Complexin II; CPX II; Synaphin-1 |
Protein Family: | Complexin |
UniProt Gene Name: | CPLX2 |
UniProt Entry Name: | CPLX2_HUMAN |