COX8A Antibody (PACO13916)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13916
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | COX8A Antibody (PACO13916) |
Antibody SKU: | PACO13916 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:10-1:50 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human COX8A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO13916(COX8A Antibody) at dilution 1/12, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO13916(COX8A Antibody) at dilution 1/12, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. |
Synonyms: | cytochrome c oxidase subunit VIIIA (ubiquitous) |
UniProt Protein Function: | COX8A: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIII family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 11q12-q13 Cellular Component: mitochondrial inner membrane; integral to membrane Molecular Function:cytochrome-c oxidase activity Biological Process: cellular metabolic process; generation of precursor metabolites and energy; transmembrane transport |
NCBI Summary: | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008] |
UniProt Code: | P10176 |
NCBI GenInfo Identifier: | 117132 |
NCBI Gene ID: | 1351 |
NCBI Accession: | P10176.2 |
UniProt Secondary Accession: | P10176,P15955, |
UniProt Related Accession: | P10176 |
Molecular Weight: | 7,579 Da |
NCBI Full Name: | Cytochrome c oxidase subunit 8A, mitochondrial |
NCBI Synonym Full Names: | cytochrome c oxidase subunit VIIIA (ubiquitous) |
NCBI Official Symbol: | COX8A |
NCBI Official Synonym Symbols: | COX; COX8; VIII; COX8L; COX8-2; VIII-L |
NCBI Protein Information: | cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase polypeptide VIII-liver/heart; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit 8A (ubiquitous); cytochrome c oxidase subunit VIII |
UniProt Protein Name: | Cytochrome c oxidase subunit 8A, mitochondrial |
UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2 |
UniProt Gene Name: | COX8A |
UniProt Entry Name: | COX8A_HUMAN |