COX4I1 Antibody (PACO25696)
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주문- SKU:
- PACO25696
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Reactivity:
- Zebrafish
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | COX4I1 Antibody (PACO25696) |
Antibody SKU: | PACO25696 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Rat, Zebrafish |
Immunogen: | Recombinant Human Cytochrome c oxidase subunit 4 isoform 1, mitochondrial protein (23-169AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: COX4I1 antibody at 10µg/ml Lane 1: Rat muscle tissue Lane 2: Zebrafish lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO25696 at dilution of 1:100. |
Background: | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. |
Synonyms: | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1), COX4I1, COX4 |
UniProt Protein Function: | COX4I1: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Ubiquitous. Belongs to the cytochrome c oxidase IV family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 1.9.3.1; Oxidoreductase Chromosomal Location of Human Ortholog: 16q24.1 Cellular Component: membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrion; nucleus Molecular Function:protein binding Biological Process: generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen |
NCBI Summary: | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
UniProt Code: | P13073 |
NCBI GenInfo Identifier: | 117086 |
NCBI Gene ID: | 1327 |
NCBI Accession: | P13073.1 |
UniProt Secondary Accession: | P13073,Q6P666, B2R4J2, D3DUM7, |
UniProt Related Accession: | P13073 |
Molecular Weight: | 19,577 Da |
NCBI Full Name: | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
NCBI Synonym Full Names: | cytochrome c oxidase subunit 4I1 |
NCBI Official Symbol: | COX4I1 |
NCBI Official Synonym Symbols: | COX4; COXIV; COX4-1; COXIV-1; COX IV-1 |
NCBI Protein Information: | cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
UniProt Protein Name: | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 |
Protein Family: | Cytochrome c oxidase |
UniProt Gene Name: | COX4I1 |
UniProt Entry Name: | COX41_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |