COL11A2 Antibody (PACO00620)
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주문- SKU:
- PACO00620
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | COL11A2 Antibody |
Antibody SKU: | PACO00620 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the C-terminal region of human COL11A2. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | COL11A2; Collagen alpha-2(XI) chain |
UniProt Protein Function: | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
NCBI Summary: | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009] |
UniProt Code: | P13942 |
NCBI GenInfo Identifier: | 374095517 |
NCBI Gene ID: | 1302 |
NCBI Accession: | P13942.5 |
UniProt Secondary Accession: | P13942,Q07751, Q13271, Q13272, Q13273, Q5JP94, Q5SUI8 Q7Z6C3, Q99866, Q9UIP9, A6NLX2, E7ER90, |
UniProt Related Accession: | P13942 |
Molecular Weight: | 172kDa |
NCBI Full Name: | Collagen alpha-2(XI) chain |
NCBI Synonym Full Names: | collagen type XI alpha 2 chain |
NCBI Official Symbol: | COL11A2 |
NCBI Official Synonym Symbols: | HKE5; PARP; STL3; FBCG2; DFNA13; DFNB53 |
NCBI Protein Information: | collagen alpha-2(XI) chain |
UniProt Protein Name: | Collagen alpha-2(XI) chain |
Protein Family: | Collagen |
UniProt Gene Name: | COL11A2 |