CMPK1 Antibody (PACO21767)
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주문- SKU:
- PACO21767
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CMPK1 Antibody (PACO21767) |
Antibody SKU: | PACO21767 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human KCY. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HeLa cells, using KCY antibody. |
Background: | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. Pearman A.T., Life Sci. 69:2361-2370(2001). |
Synonyms: | CMK; EC 2.7.4.14; KCY; RP11-511I2.1; UCK |
UniProt Protein Function: | CMPK: Catalyzes specific phosphoryl transfer from ATP to UMP and CMP. Belongs to the adenylate kinase family. |
UniProt Protein Details: | Protein type:EC 2.7.4.14; Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Kinase, other Chromosomal Location of Human Ortholog: 1p32 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:ATP binding; cytidylate kinase activity; nucleoside diphosphate kinase activity; uridine kinase activity; uridylate kinase activity Biological Process: 'de novo' pyrimidine base biosynthetic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process; pyrimidine ribonucleotide biosynthetic process; UMP biosynthetic process |
NCBI Summary: | This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012] |
UniProt Code: | P30085 |
NCBI GenInfo Identifier: | 12644008 |
NCBI Gene ID: | 51727 |
NCBI Accession: | P30085.3 |
UniProt Secondary Accession: | P30085,Q53GB7, Q5SVZ0, Q96C07, Q9UBQ8, Q9UIA2, B4DPU7 E9PGI8, |
UniProt Related Accession: | P30085 |
Molecular Weight: | 16,548 Da |
NCBI Full Name: | UMP-CMP kinase |
NCBI Synonym Full Names: | cytidine/uridine monophosphate kinase 1 |
NCBI Official Symbol: | CMPK1 |
NCBI Official Synonym Symbols: | CK; CMK; UMK; CMPK; UMPK; UMP-CMPK |
NCBI Protein Information: | UMP-CMP kinase |
UniProt Protein Name: | UMP-CMP kinase |
UniProt Synonym Protein Names: | Deoxycytidylate kinase |
UniProt Gene Name: | CMPK1 |
UniProt Entry Name: | KCY_HUMAN |