CLDN10 Antibody (PACO05679)
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주문- SKU:
- PACO05679
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CLDN10 Antibody (PACO05679) |
Antibody SKU: | PACO05679 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from the C-terminal region of human Claudin-10. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CLDN10; Claudin-10; OSP-like protein |
UniProt Protein Function: | Claudin-10: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 13q32.1 Cellular Component: tight junction Molecular Function:identical protein binding Biological Process: calcium-independent cell-cell adhesion; cell adhesion |
NCBI Summary: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010] |
UniProt Code: | P78369 |
NCBI GenInfo Identifier: | 6685311 |
NCBI Gene ID: | 9071 |
NCBI Accession: | P78369.2 |
UniProt Secondary Accession: | P78369,Q6IBF9, Q96N78, |
UniProt Related Accession: | P78369 |
Molecular Weight: | 24kDa |
NCBI Full Name: | Claudin-10 |
NCBI Synonym Full Names: | claudin 10 |
NCBI Official Symbol: | CLDN10 |
NCBI Official Synonym Symbols: | OSP-L; CPETRL3 |
NCBI Protein Information: | claudin-10 |
UniProt Protein Name: | Claudin-10 |
UniProt Synonym Protein Names: | OSP-like protein |
Protein Family: | Claudin |
UniProt Gene Name: | CLDN10 |