CKAP4 Antibody (PACO19478)
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주문- SKU:
- PACO19478
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CKAP4 Antibody (PACO19478) |
Antibody SKU: | PACO19478 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human CKAP4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T cells, hepG2 cells, A549 cells, Primary antibody: PACO19478(CKAP4 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO19478(CKAP4 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid, single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2. |
Synonyms: | cytoskeleton-associated protein 4 |
UniProt Protein Function: | CKAP4: High-affinity epithelial cell surface receptor for APF. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 12q23.3 Cellular Component: endoplasmic reticulum; lamellar body; lipid particle; membrane; plasma membrane Biological Process: cellular protein metabolic process |
UniProt Code: | Q07065 |
NCBI GenInfo Identifier: | 74735614 |
NCBI Gene ID: | 10970 |
NCBI Accession: | Q07065.2 |
UniProt Secondary Accession: | Q07065,Q504S5, Q53ES6, |
UniProt Related Accession: | Q07065 |
Molecular Weight: | 66,022 Da |
NCBI Full Name: | Cytoskeleton-associated protein 4 |
NCBI Synonym Full Names: | cytoskeleton associated protein 4 |
NCBI Official Symbol: | CKAP4 |
NCBI Official Synonym Symbols: | p63; CLIMP-63; ERGIC-63 |
NCBI Protein Information: | cytoskeleton-associated protein 4 |
UniProt Protein Name: | Cytoskeleton-associated protein 4 |
UniProt Synonym Protein Names: | 63-kDa cytoskeleton-linking membrane protein; Climp-63; p63 |
Protein Family: | Cytoskeleton-associated protein |
UniProt Gene Name: | CKAP4 |
UniProt Entry Name: | CKAP4_HUMAN |