CHRNA6 Antibody (PACO45362)
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주문- SKU:
- PACO45362
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CHRNA6 Antibody (PACO45362) |
Antibody SKU: | PACO45362 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Neuronal acetylcholine receptor subunit alpha-6 protein (26-239AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: CHRNA6 antibody at 2.29µg/ml. Lane 1: A431 whole cell lysate. Lane 2: THP-1 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 57, 56 kDa. Observed band size: 57 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO45362 at dilution of 1:100. |
Background: | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Synonyms: | Neuronal acetylcholine receptor subunit alpha-6, CHRNA6 |
UniProt Protein Function: | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
NCBI Summary: | This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010] |
UniProt Code: | Q15825 |
NCBI GenInfo Identifier: | 313482792 |
NCBI Gene ID: | 8973 |
NCBI Accession: | NP_001186208.1 |
UniProt Secondary Accession: | Q15825,B2R8V4, B4DQH1, |
UniProt Related Accession: | Q15825 |
Molecular Weight: | 54 |
NCBI Full Name: | neuronal acetylcholine receptor subunit alpha-6 isoform 2 |
NCBI Synonym Full Names: | cholinergic receptor nicotinic alpha 6 subunit |
NCBI Official Symbol: | CHRNA6 |
NCBI Official Synonym Symbols: | CHNRA6 |
NCBI Protein Information: | neuronal acetylcholine receptor subunit alpha-6 |
UniProt Protein Name: | Neuronal acetylcholine receptor subunit alpha-6 |
UniProt Gene Name: | CHRNA6 |