CHRM5 Antibody (PACO02421)
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주문- SKU:
- PACO02421
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CHRM5 Antibody |
Antibody SKU: | PACO02421 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human mAChR M5. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CHRM5; Muscarinic acetylcholine receptor M5 |
UniProt Protein Function: | mAChR M5: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. |
UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 15q26 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:phosphoinositide phospholipase C activity; G-protein coupled acetylcholine receptor activity Biological Process: dopamine transport; gastric acid secretion; cell proliferation; acetylcholine receptor signaling, muscarinic pathway; metabolic process; muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway; transmission of nerve impulse |
NCBI Summary: | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008] |
UniProt Code: | P08912 |
NCBI GenInfo Identifier: | 543761 |
NCBI Gene ID: | 1133 |
NCBI Accession: | P08912.2 |
UniProt Secondary Accession: | P08912,Q96RG7, |
UniProt Related Accession: | P08912 |
Molecular Weight: | 532 |
NCBI Full Name: | Muscarinic acetylcholine receptor M5 |
NCBI Synonym Full Names: | cholinergic receptor, muscarinic 5 |
NCBI Official Symbol: | CHRM5 |
NCBI Official Synonym Symbols: | HM5 |
NCBI Protein Information: | muscarinic acetylcholine receptor M5; acetylcholine receptor, muscarinic 5 |
UniProt Protein Name: | Muscarinic acetylcholine receptor M5 |
Protein Family: | Muscarinic acetylcholine receptor |
UniProt Gene Name: | CHRM5 |
UniProt Entry Name: | ACM5_HUMAN |