CHD4 Antibody (PACO23246)
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주문- SKU:
- PACO23246
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CHD4 Antibody (PACO23246) |
Antibody SKU: | PACO23246 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human CHD4. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 antibody. |
![]() | Immunofluorescence analysis of HepG2 cells, using CHD4 antibody. |
Background: | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. |
Synonyms: | EC 3.6.1.-; ATP-dependent helicase CHD4; CHD-4; Mi-2 autoantigen 218 kDa protein; Mi2-beta |
UniProt Protein Function: | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. |
NCBI Summary: | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
UniProt Code: | Q14839 |
NCBI GenInfo Identifier: | 311033360 |
NCBI Gene ID: | 1108 |
NCBI Accession: | Q14839.2 |
UniProt Secondary Accession: | Q14839,Q8IXZ5, |
UniProt Related Accession: | Q14839 |
Molecular Weight: | 278 kDa |
NCBI Full Name: | Chromodomain-helicase-DNA-binding protein 4 |
NCBI Synonym Full Names: | chromodomain helicase DNA binding protein 4 |
NCBI Official Symbol: | CHD4 |
NCBI Official Synonym Symbols: | CHD-4; Mi-2b; SIHIWES; Mi2-BETA |
NCBI Protein Information: | chromodomain-helicase-DNA-binding protein 4 |
UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 4 |
UniProt Synonym Protein Names: | ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta |
Protein Family: | Chromodomain-helicase-DNA-binding protein |
UniProt Gene Name: | CHD4 |