CHD1L Antibody (PACO01746)
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주문- SKU:
- PACO01746
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CHD1L Antibody |
Antibody SKU: | PACO01746 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human CHD1L. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CHD1L; ALC1; Chromodomain-helicase-DNA-binding protein 1-like; Amplified in liver cancer protein 1 |
UniProt Protein Function: | CHD1L: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. Belongs to the SNF2/RAD54 helicase family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.6.4.12; Helicase; DNA-binding Chromosomal Location of Human Ortholog: 1q12 Cellular Component: cytoplasm; nucleoplasm; nucleus; plasma membrane Molecular Function:ATP-dependent DNA helicase activity; ATPase activity; nucleotide binding; protein binding Biological Process: chromatin remodeling; DNA repair; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, preincision complex stabilization; response to DNA damage stimulus |
NCBI Summary: | This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q86WJ1 |
NCBI GenInfo Identifier: | 311033359 |
NCBI Gene ID: | 9557 |
NCBI Accession: | Q86WJ1.2 |
UniProt Secondary Accession: | Q86WJ1,Q53EZ3, Q5VXX7, Q6DD94, Q6PK83, Q86XH3, Q96HF7 Q96SP3, Q9BVJ1, A5YM64, B4DDE1, B5MDZ7, |
UniProt Related Accession: | Q86WJ1 |
Molecular Weight: | 69,139 Da |
NCBI Full Name: | Chromodomain-helicase-DNA-binding protein 1-like |
NCBI Synonym Full Names: | chromodomain helicase DNA binding protein 1 like |
NCBI Official Symbol: | CHD1L |
NCBI Official Synonym Symbols: | ALC1; CHDL |
NCBI Protein Information: | chromodomain-helicase-DNA-binding protein 1-like |
UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 1-like |
UniProt Synonym Protein Names: | Amplified in liver cancer protein 1 |
Protein Family: | Chromodomain-helicase-DNA-binding protein |
UniProt Gene Name: | CHD1L |
UniProt Entry Name: | CHD1L_HUMAN |