CER1 Antibody (PACO43656)
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주문- SKU:
- PACO43656
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | CER1 Antibody (PACO43656) |
Antibody SKU: | PACO43656 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Cerberus protein (18-267AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Cerberus antibody at 2µg/ml. Lane 1: Hela whole cell lysate. Lane 2: Rat kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 30 kDa. Observed band size: 30 kDa. |
Background: | Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity). |
Synonyms: | Cerberus (Cerberus-related protein) (DAN domain family member 4), CER1, DAND4 |
UniProt Protein Function: | CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted Chromosomal Location of Human Ortholog: 9p23-p22 Cellular Component: extracellular space; extracellular region Molecular Function:morphogen activity; protein homodimerization activity; cytokine activity Biological Process: BMP signaling pathway; anterior/posterior pattern formation; negative regulation of cell proliferation; nervous system development; negative regulation of activin receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud development; gastrulation; determination of dorsal identity; bone mineralization; cell migration involved in gastrulation; negative regulation of BMP signaling pathway; anterior/posterior axis specification |
NCBI Summary: | This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95813 |
NCBI GenInfo Identifier: | 62510411 |
NCBI Gene ID: | 9350 |
NCBI Accession: | O95813.1 |
UniProt Related Accession: | O95813 |
Molecular Weight: | |
NCBI Full Name: | Cerberus |
NCBI Synonym Full Names: | cerberus 1, DAN family BMP antagonist |
NCBI Official Symbol: | CER1 |
NCBI Official Synonym Symbols: | DAND4 |
NCBI Protein Information: | cerberus |
UniProt Protein Name: | Cerberus |
UniProt Synonym Protein Names: | Cerberus-related protein; DAN domain family member 4 |
UniProt Gene Name: | CER1 |
UniProt Entry Name: | CER1_HUMAN |