CENPQ Antibody (PACO43934)
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주문- SKU:
- PACO43934
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CENPQ Antibody (PACO43934) |
Antibody SKU: | PACO43934 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Centromere protein Q protein (131-268AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO43934 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO43934 at dilution of 1:100. |
Background: | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. |
Synonyms: | Centromere protein Q (CENP-Q), CENPQ, C6orf139 |
UniProt Protein Function: | CENPQ: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p12.3 Cellular Component: nucleoplasm; cytosol; chromosome, pericentric region; actin cytoskeleton Biological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; mitotic cell cycle |
NCBI Summary: | CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q7L2Z9 |
NCBI GenInfo Identifier: | 40068061 |
NCBI Gene ID: | 55166 |
NCBI Accession: | NP_060602.2 |
UniProt Secondary Accession: | Q7L2Z9,Q6IN61, Q9NVS5, A8KAF1, |
UniProt Related Accession: | Q7L2Z9 |
Molecular Weight: | 30,595 Da |
NCBI Full Name: | centromere protein Q |
NCBI Synonym Full Names: | centromere protein Q |
NCBI Official Symbol: | CENPQ |
NCBI Official Synonym Symbols: | CENP-Q; C6orf139 |
NCBI Protein Information: | centromere protein Q |
UniProt Protein Name: | Centromere protein Q |
Protein Family: | Centromere protein |
UniProt Gene Name: | CENPQ |
UniProt Entry Name: | CENPQ_HUMAN |
Antibodies |
Anti-CENPQ Antibody (CAB7628) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |