CELF6 Antibody (PACO61069)
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주문- SKU:
- PACO61069
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CELF6 Antibody (PACO61069) |
Antibody SKU: | PACO61069 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human CUGBP Elav-like family member 6 protein (292-395AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate, PC-3 whole cell lysate. All lanes: CELF6 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 51, 39, 48, 37 kDa. Observed band size: 51 kDa. |
Background: | RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA. |
Synonyms: | CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6), CELF6, BRUNOL6 |
NCBI Summary: | Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010] |
UniProt Code: | Q96J87 |
NCBI GenInfo Identifier: | 70780381 |
NCBI Gene ID: | 60677 |
NCBI Accession: | NP_443072 |
UniProt Related Accession: | Q96J87 |
Molecular Weight: | 50kDa |
NCBI Full Name: | CUGBP Elav-like family member 6 isoform 1 |
NCBI Synonym Full Names: | CUGBP Elav-like family member 6 |
NCBI Official Symbol: | CELF6 |
NCBI Official Synonym Symbols: | BRUNOL6 |
NCBI Protein Information: | CUGBP Elav-like family member 6 |
UniProt Protein Name: | CUGBP Elav-like family member 6 |
UniProt Synonym Protein Names: | Bruno-like protein 6; CUG-BP- and ETR-3-like factor 6; RNA-binding protein BRUNOL-6 |
Protein Family: | CUGBP Elav-like family |
UniProt Gene Name: | CELF6 |
UniProt Entry Name: | CELF6_HUMAN |