CDX1 Antibody (PACO51410)
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주문- SKU:
- PACO51410
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CDX1 Antibody (PACO51410) |
Antibody SKU: | PACO51410 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Homeobox protein CDX-1 protein (206-245AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat liver tissue. All lanes: CDX1 antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 29, 15 kDa. Observed band size: 29 kDa.. |
![]() | Immunofluorescent analysis of Hela cells using PACO51410 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. |
Synonyms: | Homeobox protein CDX-1 (Caudal-type homeobox protein 1), CDX1 |
UniProt Protein Function: | CDX1: Could play a role in the terminal differentiation of the intestine. Belongs to the Caudal homeobox family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 5q32 Cellular Component: nucleus Molecular Function:protein binding Biological Process: anterior/posterior axis specification; cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of somitogenesis |
NCBI Summary: | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | P47902 |
NCBI GenInfo Identifier: | 116241291 |
NCBI Gene ID: | 1044 |
NCBI Accession: | P47902.2 |
UniProt Secondary Accession: | P47902,Q4VAU4, Q9NYK8, |
UniProt Related Accession: | P47902 |
Molecular Weight: | 14,661 Da |
NCBI Full Name: | Homeobox protein CDX-1 |
NCBI Synonym Full Names: | caudal type homeobox 1 |
NCBI Official Symbol: | CDX1 |
NCBI Protein Information: | homeobox protein CDX-1 |
UniProt Protein Name: | Homeobox protein CDX-1 |
UniProt Synonym Protein Names: | Caudal-type homeobox protein 1 |
Protein Family: | Homeobox protein |
UniProt Gene Name: | CDX1 |
UniProt Entry Name: | CDX1_HUMAN |
Antibodies |
Anti-CDX1 Antibody (CAB5712) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |