CDH17 Antibody (PACO02300)
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주문- SKU:
- PACO02300
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CDH17 Antibody |
Antibody SKU: | PACO02300 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human LI-cadherin. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CDH17; Cadherin-17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
UniProt Protein Function: | CDH17: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 8q22.1 Cellular Component: basolateral plasma membrane; plasma membrane; integral to membrane Molecular Function:transporter activity; calcium ion binding; proton-dependent oligopeptide secondary active transmembrane transporter activity Biological Process: intercellular junction assembly and maintenance; transport; calcium-dependent cell-cell adhesion; cell adhesion; oligopeptide transport; homophilic cell adhesion |
NCBI Summary: | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
UniProt Code: | Q12864 |
NCBI GenInfo Identifier: | 308153624 |
NCBI Gene ID: | 1015 |
NCBI Accession: | Q12864.3 |
UniProt Secondary Accession: | Q12864,Q15336, Q2M2E0, |
UniProt Related Accession: | Q12864 |
Molecular Weight: | 92,219 Da |
NCBI Full Name: | Cadherin-17 |
NCBI Synonym Full Names: | cadherin 17, LI cadherin (liver-intestine) |
NCBI Official Symbol: | CDH17 |
NCBI Official Synonym Symbols: | HPT1; CDH16; HPT-1 |
NCBI Protein Information: | cadherin-17; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestinal peptide-associated transporter HPT-1 |
UniProt Protein Name: | Cadherin-17 |
UniProt Synonym Protein Names: | Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
Protein Family: | Cadherin |
UniProt Gene Name: | CDH17 |
UniProt Entry Name: | CAD17_HUMAN |