CDCA4 Antibody (PACO19455)
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주문- SKU:
- PACO19455
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CDCA4 Antibody (PACO19455) |
Antibody SKU: | PACO19455 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human CDCA4 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO19455(CDCA4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19455(CDCA4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. |
Synonyms: | cell division cycle associated 4 |
UniProt Protein Function: | CDCA4: May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation. |
UniProt Protein Details: | Protein type:Transcription regulation Chromosomal Location of Human Ortholog: 14q32.33 Cellular Component: nucleus Molecular Function:protein binding |
NCBI Summary: | This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014] |
UniProt Code: | Q9BXL8 |
NCBI GenInfo Identifier: | 32699606 |
NCBI Gene ID: | 55038 |
NCBI Accession: | Q9BXL8.1 |
UniProt Secondary Accession: | Q9BXL8,Q8TB18, Q9NWK7, |
UniProt Related Accession: | Q9BXL8 |
Molecular Weight: | 26,114 Da |
NCBI Full Name: | Cell division cycle-associated protein 4 |
NCBI Synonym Full Names: | cell division cycle associated 4 |
NCBI Official Symbol: | CDCA4 |
NCBI Official Synonym Symbols: | HEPP; SEI-3/HEPP |
NCBI Protein Information: | cell division cycle-associated protein 4 |
UniProt Protein Name: | Cell division cycle-associated protein 4 |
UniProt Synonym Protein Names: | Hematopoietic progenitor protein |
Protein Family: | Cell division cycle-associated protein |
UniProt Gene Name: | CDCA4 |
UniProt Entry Name: | CDCA4_HUMAN |