CD5L Antibody (PACO19442)
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주문- SKU:
- PACO19442
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CD5L Antibody (PACO19442) |
Antibody SKU: | PACO19442 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human CD5L |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19442(CD5L Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human Lymphoma tissue using PACO19442(CD5L Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | CD5L (CD5 molecule-like), also known as API6, PRO229, Spα or SP-ALPHA, is a 347 amino acid, secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival. |
Synonyms: | CD5 molecule-like |
UniProt Protein Function: | CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis. |
UniProt Protein Details: | Protein type:Receptor, misc.; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 1q23.1 Cellular Component: extracellular space; membrane; extracellular region Molecular Function:scavenger receptor activity Biological Process: receptor-mediated endocytosis; apoptosis; cellular defense response |
UniProt Code: | O43866 |
NCBI GenInfo Identifier: | 20177834 |
NCBI Gene ID: | 922 |
NCBI Accession: | O43866.1 |
UniProt Secondary Accession: | O43866,Q6UX63, A8K7M5, |
UniProt Related Accession: | O43866 |
Molecular Weight: | 347 |
NCBI Full Name: | CD5 antigen-like |
NCBI Synonym Full Names: | CD5 molecule-like |
NCBI Official Symbol: | CD5L |
NCBI Official Synonym Symbols: | AIM; API6; PRO229; Spalpha; SP-ALPHA |
NCBI Protein Information: | CD5 antigen-like; CT-2; apoptosis inhibitor 6; igM-associated peptide; CD5 antigen-like (scavenger receptor cysteine rich family) |
UniProt Protein Name: | CD5 antigen-like |
UniProt Synonym Protein Names: | CT-2; IgM-associated peptide; SP-alpha |
Protein Family: | CD5 antigen |
UniProt Gene Name: | CD5L |
UniProt Entry Name: | CD5L_HUMAN |
Antibodies | ELISA Kits |
Anti-CD5L Antibody (CAB6223) | Human CD5L ELISA Kit |
Human CD5 antigen-like (CD5L) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |