CCT7 Antibody (PACO22648)
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주문- SKU:
- PACO22648
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CCT7 Antibody (PACO22648) |
Antibody SKU: | PACO22648 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CCT7. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HeLa cells, using CCT7 antibody. |
Background: | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin By similarity. |
Synonyms: | TCP-1-eta; CCT-eta; HIV-1 Nef-interacting protein; CCTH; NIP7-1 |
UniProt Protein Function: | CCT7: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 2p13.2 Cellular Component: chaperonin-containing T-complex; cytoplasm; cytosol; microtubule Molecular Function:protein binding; unfolded protein binding Biological Process: 'de novo' protein folding; positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization |
NCBI Summary: | This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q99832 |
NCBI GenInfo Identifier: | 3041738 |
NCBI Gene ID: | 10574 |
NCBI Accession: | Q99832.2 |
UniProt Secondary Accession: | Q99832,O14871, Q6FI26, A8K7E6, A8MWI8, B7WNW9, B7Z4T9 B7Z4Z7, |
UniProt Related Accession: | Q99832 |
Molecular Weight: | 59kDa |
NCBI Full Name: | T-complex protein 1 subunit eta |
NCBI Synonym Full Names: | chaperonin containing TCP1 subunit 7 |
NCBI Official Symbol: | CCT7 |
NCBI Official Synonym Symbols: | CCTH; CCTETA; NIP7-1; TCP1ETA |
NCBI Protein Information: | T-complex protein 1 subunit eta |
UniProt Protein Name: | T-complex protein 1 subunit eta |
UniProt Synonym Protein Names: | CCT-eta; HIV-1 Nef-interacting protein |
Protein Family: | Probable T-complex protein |
UniProt Gene Name: | CCT7 |