CCNB2 Antibody (PACO17761)
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주문- SKU:
- PACO17761
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CCNB2 Antibody (PACO17761) |
Antibody SKU: | PACO17761 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human CCNB2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17761(CCNB2 Antibody) at dilution 1/10, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor β RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. |
Synonyms: | cyclin B2 |
UniProt Protein Function: | CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; membrane; cytosol Molecular Function:protein binding; protein kinase binding Biological Process: mitosis; thymus development; cell division; regulation of cell cycle; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth |
NCBI Summary: | Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95067 |
NCBI GenInfo Identifier: | 5921731 |
NCBI Gene ID: | 9133 |
NCBI Accession: | O95067.1 |
UniProt Related Accession: | O95067 |
Molecular Weight: | ~ 45kDa |
NCBI Full Name: | G2/mitotic-specific cyclin-B2 |
NCBI Synonym Full Names: | cyclin B2 |
NCBI Official Symbol: | CCNB2 |
NCBI Official Synonym Symbols: | HsT17299 |
NCBI Protein Information: | G2/mitotic-specific cyclin-B2 |
UniProt Protein Name: | G2/mitotic-specific cyclin-B2 |
Protein Family: | Light-harvesting protein |
UniProt Gene Name: | CCNB2 |
UniProt Entry Name: | CCNB2_HUMAN |