CCL17 Antibody (PACO17666)
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주문- SKU:
- PACO17666
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CCL17 Antibody (PACO17666) |
Antibody SKU: | PACO17666 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human CCL17 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO17666(CCL17 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 15%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse lung tissue, Mouse thymus tissue, human fetal muscle tissue, Primary antibody: PACO17666(CCL17 Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 45 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17666(CCL17 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. |
Synonyms: | chemokine (C-C motif) ligand 17 |
UniProt Protein Function: | CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16q13 Cellular Component: extracellular space; extracellular region Molecular Function:CCR4 chemokine receptor binding; chemokine activity; receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; multicellular organismal development; immune response; chemotaxis; inflammatory response; negative regulation of myoblast differentiation |
NCBI Summary: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q92583 |
NCBI GenInfo Identifier: | 3024711 |
NCBI Gene ID: | 6361 |
NCBI Accession: | Q92583.1 |
UniProt Secondary Accession: | Q92583,Q2M287, A0N0Q9, |
UniProt Related Accession: | Q92583 |
Molecular Weight: | 10,507 Da |
NCBI Full Name: | C-C motif chemokine 17 |
NCBI Synonym Full Names: | chemokine (C-C motif) ligand 17 |
NCBI Official Symbol: | CCL17 |
NCBI Official Synonym Symbols: | TARC; ABCD-2; SCYA17; A-152E5.3 |
NCBI Protein Information: | C-C motif chemokine 17; CC chemokine TARC; T cell-directed CC chemokine; small-inducible cytokine A17; thymus and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 17 |
UniProt Protein Name: | C-C motif chemokine 17 |
UniProt Synonym Protein Names: | CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine |
UniProt Gene Name: | CCL17 |
UniProt Entry Name: | CCL17_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |