CBR3 Antibody (PACO23407)
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주문- SKU:
- PACO23407
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CBR3 Antibody (PACO23407) |
Antibody SKU: | PACO23407 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human CBR3. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from MCF7 cells and Jurkat cells, using CBR3 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CBR3 antibody. |
Background: | Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). |
Synonyms: | carbonyl reductase 3; EC 1.1.1.184; NADPH-dependent carbonyl reductase 3; |
UniProt Protein Function: | CBR3: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
UniProt Protein Details: | Protein type:Oxidoreductase; Lipid Metabolism - arachidonic acid; EC 1.1.1.184 Chromosomal Location of Human Ortholog: 21q22.2 Cellular Component: cytoplasm; cytosol; extracellular space; nucleoplasm Molecular Function:3-keto sterol reductase activity; carbonyl reductase (NADPH) activity Biological Process: cognition; phylloquinone catabolic process |
NCBI Summary: | Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75828 |
NCBI GenInfo Identifier: | 6014959 |
NCBI Gene ID: | 874 |
NCBI Accession: | O75828.3 |
UniProt Secondary Accession: | O75828,Q6FHP2, |
UniProt Related Accession: | O75828 |
Molecular Weight: | 30,850 Da |
NCBI Full Name: | Carbonyl reductase |
NCBI Synonym Full Names: | carbonyl reductase 3 |
NCBI Official Symbol: | CBR3 |
NCBI Official Synonym Symbols: | hCBR3; SDR21C2; HEL-S-25 |
NCBI Protein Information: | carbonyl reductase [NADPH] 3 |
UniProt Protein Name: | Carbonyl reductase [NADPH] 3 |
UniProt Synonym Protein Names: | NADPH-dependent carbonyl reductase 3; Short chain dehydrogenase/reductase family 21C member 2 |
Protein Family: | Carbonyl reductase |
UniProt Gene Name: | CBR3 |
UniProt Entry Name: | CBR3_HUMAN |