CAPZA1 Antibody (PACO19387)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO19387
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CAPZA1 Antibody (PACO19387) |
Antibody SKU: | PACO19387 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human CAPZA1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19387(CAPZA1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19387(CAPZA1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | CAPZA1 is a member of the F-actin capping protein α subunit family. This gene encodes the α subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
Synonyms: | capping protein (actin filament) muscle Z-line, α 1 |
UniProt Protein Function: | CAPZA1: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Belongs to the F-actin-capping protein alpha subunit family. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: F-actin capping protein complex; cytoskeleton; extracellular region; cytosol; actin cytoskeleton Molecular Function:protein binding; actin binding Biological Process: innate immune response; protein complex assembly; cell motility; blood coagulation; barbed-end actin filament capping |
NCBI Summary: | CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52907 |
NCBI GenInfo Identifier: | 1705650 |
NCBI Gene ID: | 829 |
NCBI Accession: | P52907.3 |
UniProt Secondary Accession: | P52907,Q53FQ6, Q6FHD5, |
UniProt Related Accession: | P52907 |
Molecular Weight: | 286 |
NCBI Full Name: | F-actin-capping protein subunit alpha-1 |
NCBI Synonym Full Names: | capping protein (actin filament) muscle Z-line, alpha 1 |
NCBI Official Symbol: | CAPZA1 |
NCBI Official Synonym Symbols: | CAPZ; CAZ1; CAPPA1 |
NCBI Protein Information: | F-actin-capping protein subunit alpha-1; Cap Z; capZ alpha-1 |
UniProt Protein Name: | F-actin-capping protein subunit alpha-1 |
UniProt Synonym Protein Names: | CapZ alpha-1 |
Protein Family: | F-actin-capping protein |
UniProt Gene Name: | CAPZA1 |
UniProt Entry Name: | CAZA1_HUMAN |