CADM2 Antibody (PACO22022)
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주문- SKU:
- PACO22022
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CADM2 Antibody (PACO22022) |
Antibody SKU: | PACO22022 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human CADM2. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HepG2 cells, using CADM2 antibody. |
Background: | Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. |
Synonyms: | Cell adhesion molecule 2 [Precursor]; Immunoglobulin superfamily member 4D; Nectin-like protein 3; CADM2; IGSF4D |
UniProt Protein Function: | CADM2: Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 3p12.1 Cellular Component: axon; cell-cell adherens junction; integral to plasma membrane; plasma membrane; synapse Molecular Function:cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; intercellular junction assembly and maintenance |
NCBI Summary: | This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q8N3J6 |
NCBI GenInfo Identifier: | 74759850 |
NCBI Gene ID: | 253559 |
NCBI Accession: | Q8N3J6.1 |
UniProt Secondary Accession: | Q8N3J6,Q3KQY9, Q658Q7, Q8IZP8, G3XHN7, G3XHN8, |
UniProt Related Accession: | Q8N3J6 |
Molecular Weight: | 35,410 Da |
NCBI Full Name: | Cell adhesion molecule 2 |
NCBI Synonym Full Names: | cell adhesion molecule 2 |
NCBI Official Symbol: | CADM2 |
NCBI Official Synonym Symbols: | NECL3; IGSF4D; Necl-3; synCAM2; SynCAM 2 |
NCBI Protein Information: | cell adhesion molecule 2 |
UniProt Protein Name: | Cell adhesion molecule 2 |
UniProt Synonym Protein Names: | Immunoglobulin superfamily member 4D; IgSF4D; Nectin-like protein 3; NECL-3; Synaptic cell adhesion molecule 2; SynCAM 2 |
Protein Family: | Cell adhesion molecule |
UniProt Gene Name: | CADM2 |
UniProt Entry Name: | CADM2_HUMAN |