CACNG7 Antibody (PACO01031)
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주문- SKU:
- PACO01031
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CACNG7 Antibody |
Antibody SKU: | PACO01031 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the C-terminal region of human L-type Ca++ CP gamma7. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CACNG7; Voltage-dependent calcium channel gamma-7 subunit; Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7 |
UniProt Protein Function: | CACNG7: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Channel, calcium; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: plasma membrane Molecular Function:channel regulator activity; voltage-gated calcium channel activity Biological Process: transmission of nerve impulse |
NCBI Summary: | The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010] |
UniProt Code: | P62955 |
NCBI GenInfo Identifier: | 109730502 |
NCBI Gene ID: | 59284 |
NCBI Accession: | BC113503 |
UniProt Secondary Accession: | P62955,Q52LL8, Q8VBX3, Q8WXS6, Q9BXT1, |
UniProt Related Accession: | P62955 |
Molecular Weight: | 31,003 Da |
NCBI Full Name: | Homo sapiens calcium channel, voltage-dependent, gamma subunit 7, mRNA |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 7 |
NCBI Official Symbol: | CACNG7 |
NCBI Protein Information: | voltage-dependent calcium channel gamma-7 subunit |
UniProt Protein Name: | Voltage-dependent calcium channel gamma-7 subunit |
UniProt Synonym Protein Names: | Neuronal voltage-gated calcium channel gamma-7 subunit; Transmembrane AMPAR regulatory protein gamma-7; TARP gamma-7 |
Protein Family: | Voltage-dependent calcium channel |
UniProt Gene Name: | CACNG7 |
UniProt Entry Name: | CCG7_HUMAN |