CACNA2D4 Antibody (PACO00495)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO00495
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | CACNA2D4 Antibody |
Antibody SKU: | PACO00495 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from the Internal region of human Cacna2d4. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | CACNA2D4; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-gated calcium channel subunit alpha-2/delta-4 |
UniProt Protein Function: | CACNA2D4: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Defects in CACNA2D4 are the cause of retinal cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity. Belongs to the calcium channel subunit alpha-2/delta family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Channel, calcium; Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.33 Cellular Component: plasma membrane; voltage-gated calcium channel complex Molecular Function:voltage-gated calcium channel activity Biological Process: detection of light stimulus involved in visual perception Disease: Retinal Cone Dystrophy 4 |
NCBI Summary: | This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q7Z3S7 |
NCBI GenInfo Identifier: | 296434419 |
NCBI Gene ID: | 93589 |
NCBI Accession: | Q7Z3S7.2 |
UniProt Secondary Accession: | Q7Z3S7,Q7Z3S8, Q86XZ5, Q8IZS9, |
UniProt Related Accession: | Q7Z3S7 |
Molecular Weight: | 128kDa |
NCBI Full Name: | Voltage-dependent calcium channel subunit alpha-2/delta-4 |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit alpha2delta 4 |
NCBI Official Symbol: | CACNA2D4 |
NCBI Official Synonym Symbols: | RCD4 |
NCBI Protein Information: | voltage-dependent calcium channel subunit alpha-2/delta-4 |
UniProt Protein Name: | Voltage-dependent calcium channel subunit alpha-2/delta-4 |
UniProt Synonym Protein Names: | Voltage-gated calcium channel subunit alpha-2/delta-4 |
Protein Family: | Voltage-dependent calcium channel |
UniProt Gene Name: | CACNA2D4 |